Mediastinal Myxoid Neurofibroma: Unusual Location of a Rare Disease

Myxoid neurofibroma (MN) is a benign tumor of the peripheral nerves arising from connective tissue cells. This is a rare tumor characterized by immunostaining for S-100 protein [1]. From its nervous origin, its topography is fairly diverse. The most common locations of the MN are the face, shoulders, arms, periungual and in the feet. Mediastinal location has not yet been described. Through observation, to our knowledge, we report the first case of mediastinal location of a myxoid neurofibroma and discuss the diagnostic approach.